Can We Increase Survival of Patients with Gastric Cancer?
Researchers have identified factors that affect life expectancy of patients with stomach cancer, reported in the December issue of Clinical Gastroenterology and Hepatology. Use of these factors to...
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Can We Treat Diarrhea by Stimulating Na+ Absorption?
Drugs designed to increase intestinal absorption of sodium might be the best approach for treatment of diarrheal diseases, according to the Advances in Translational Science article in the January...
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Are IBD Drugs Safe During Pregnancy?
Researchers find no evidence that inflammatory bowel disease (IBD) during pregnancy, or medical treatment for IBD during pregnancy, increases risk for congenital abnormalities in children. The...
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In Treating Crohn’s Disease, Earlier is Better
Patients receiving medical therapies when they have more complicated stages of Crohn’s disease (CD) are more likely to require surgery, researchers report in the March issue of Clinical...
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What is the Best Way to Care for Patients with Alcoholic Hepatitis?
Although alcohol-related liver disease is the 8th most common cause of mortality in the US and the 2nd leading cause of mortality among all gastrointestinal diseases, there are few therapeutic options...
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Does Getting Rid of H pylori Stop Gastric Cancer’s Return?
Eradication of Helicobacter pylori after endoscopic resection of gastric lesions doesn’t prevent later development of new stomach tumors, researchers report in the May issue of Clinical...
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Can a Vaccine Prevent Pancreatic Cancer Progression?
Researchers have developed immunotherapy to slow progression of early-stage pancreatic tumors in mice. This approach might be developed to prevent progression of premalignant lesions to PDA,...
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Meeting Report: 20th International Symposium on Hepatitis C Virus and Related...
Didn’t make it to the 20th International Symposium on HCV and Related Viruses last fall in Melbourne, Australia? No worries—you can read a summary of the key findings presented at the meeting in the...
View ArticleDoes Thiopurine Therapy for IBD Increase Risk of Acute Myeloid Leukemias and...
Past exposure to thiopurines increases the risk of myeloid disorders 7-fold among patients with inflammatory bowel diseases (IBDs), according to a prospective study in the August issue of Clinical...
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How Do NS5A Inhibitors Prevent HCV Replication?
Researchers have uncovered the mechanisms of drugs that inhibit the hepatitis C virus (HCV) non-structural protein 5A (NS5A), described in the August issue of Gastroenterology. In a quantitative...
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Podcast: Efficacy of Vedolizumab in Patients with Moderately to Severely...
Listen to Bruce Sands discuss his article in the September issue of Gastroenterology discussing results from placebo-controlled, phase 3 double-blind trial of the efficacy of vedolizumab in patients...
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FDA Approves New Obesity Drug
The US Food and Drug Administration (FDA) approved the third new prescription drug for obesity since 2012. The drug, Contrave, to be used along with a low-calorie diet and exercise regimen, was...
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Video: Risk of Upper Gastrointestinal Bleeding From Different Drug Combinations
Combined use of nonselective nonsteroidal anti-inflammatory drugs (nNSAIDs), COX-2 selective inhibitors, or low-dose aspirin with selective serotonin reuptake inhibitors significantly increases the...
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Can Mesalamine Prevent Diverticulitis Recurrence?
Mesalamine is no better than placebo in preventing recurrent diverticulitis, and is not recommended for its treatment, researchers conclude from 2 international phase 3 studies. The findings are...
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Bone Tumors, Abdominal Pain, and Aspirin
Physicians report an unusual case of a man with abdominal pain that responded to aspirin therapy, in the October issue of Gastroenterology. It turns out that the pain was caused by a...
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Curbing Crohn’s for the Long Term?
Most people with Crohn’s disease receive surgery, yet the disease comes back a short time later. A study in the July issue of Clinical Gastroenterology and Hepatology reports that giving patients low...
View ArticleNew Word on GERD?
Proton pump inhibitors (PPIs) are useful for treating gastroesophageal reflux disease (GERD), although heartburn completely resolves in only 40% of patients that take these drugs. Furthermore,...
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Tracking Crohn’s Therapy
Measuring blood levels of C-reactive protein (CRP), a marker of inflammation, is a good way to monitor recovery from Crohn’s disease (CD) in patients being treated with infliximab, according to...
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Coffee Therapy for Hepatitis C?
Drinking 3 cups of coffee a day helps patients with hepatitis C respond to treatment, report Neal Freedman et al. in the June issue of Gastroenterology. Coffee reduces risks of progression of liver...
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Does Mucosal Healing Determine Which Patients Will Recover From Ulcerative...
Lack of mucosal healing, based on endoscopic analysis, identifies patients with ulcerative colitis (UC) who are not likely to respond to corticosteroid therapy, according to Sandro Ardizzone et al. in...
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